| Event | Time | Participant(s) | Year |
| 100-Meter Dash | 11.85 | Callen Martin | May 8, 2009 |
| 200-Meter Dash | 24.80 | Callen Martin | May 8, 2009 |
| 400-Meter Dash | 56.12 | Dana Crow | May 24, 2002 |
| 800-Meter Run | 2:14.52 | Brittany Wolf | April 28, 2001 |
| 1,500-Meter Run | 4:53.70 | Tricia Steffan | April 5, 2014 |
| Steeplechase | 11:36.28 | Annie Cekada | April 14, 2012 |
| 5,000-Meter Run | 17:40.55 | Jenna Parlette | May 9, 2013 |
| 10,000-Meter Run | 37:11.29 | Jenna Parlette | April 26, 2013 |
| 110HH | 14.74 | Sarah Murphy | April 25, 2015 |
| 400IH | 1:03.30 | Denise Reinhard | May 11, 2002 |
| 400-Meter Relay | 48.71 | Rose Bataille, Brooke Cotrell, Dana Crow, Denise Reinhard | April 26, 2002 |
| 1,600-Meter Relay | 3:52.20 | Dana Crow, Brooke Cotrell, Emily Herring, Denise Reinhard | May 11, 2002 |
| 3,200-Meter Relay | 9:50.65 | Kelsey Stief, Anna Foote, Colleen Romeo, Ashley Mast | April 29, 2011 |
| 800-Meter Relay | 1:45.00 | Dana Crow, Denise Reinhard, Rose Bataille, Brooke Cotrell | March 29, 2002 |
| Sprint Medley (200-200-400-800) | 4:13.67 | Dana Crow, Denise Reinhard, Emily Herring, Brittany Wolf | March 31, 2001 |
| Distance Medley | 13:34.70 | Jessica Unger, Kara Braun, Crystal Simpson, Rachel Gullett | March 31, 2001 |
| High Jump | 5-8.5 | Emily Herring | April 20, 2002 |
| Pole Vault | 12-10.25 | Ashley Johnson | April 21, 2007 |
| Long Jump | 18-6.5 | Callen Martin | April 24, 2009 |
| Triple Jump | 41-1.75 | Doreen Nagawa | May 27, 2005 |
| Shot Put | 45-10.75 | Marissa Bolen | April 25, 2015 |
| Discus | 154-3 | Gilliane Roberts | March 29, 1998 |
| Hammer | 165-11.7 | Kayli Sullivan | March 27, 2021 |
| Javelin | 137-5 | Keri Crist | April 12, 1996 |
| Decathalon | 4,277 pts. | Sarah Murphy | April 4, 2015 |
*The office of athletic communications makes a concerted effort to keep these records accurate. If you have information that could assist this page, please contact Mitch Blankespoor, director of athletic communications, at mitch_blankespoor@wilmington.edu.
*Last updated - March 30, 2021