| Event | Time | Participant(s) | Year |
| 45-Meter Dash | 6.60 | Paula Smith | 1994 |
| 55-Meter Dash | 6.98 | Callen Martin | Feb. 27, 2010 |
| 60-Meter Dash | 7.58 | Callen Martin | Feb. 19, 2010 |
| 200-Meter Dash (>200m) | 26.44 | Susan Cluxton | Dec. 12, 1998 |
| 200-Meter Dash (=<200m) | 25.41 | Callen Martin | Feb. 27, 2010 |
| 300-Meter Dash (=<200m) | 41.52 | Dana Crow | March 2, 2002 |
| 400-Meter Dash (=<200m) | 59.70 | Emily Herring | March 7, 2003 |
| 500-Meter Run | 1:18.92 | Emily Herring | Feb. 28, 2003 |
| 600-Meter Run | 1:43.16 | Brittany Wolf | Jan. 29, 2000 |
| 800-Meter Run | 2:17.64 | Emily Herring | Feb. 28, 2003 |
| 1,000-Meter Run | 3:07.06 | Brittany Wolf | Feb. 23, 2001 |
| 1,500-Meter Run | 5:01.71 | Jessica Unger | Feb. 18, 2000 |
| Mile Run | 5:17.54 | Tricia Steffen | Feb. 22, 2014 |
| 3,000-Meter Run | 10:35.74 | Brittany Gibbons | Dec. 10, 2011 |
| 5,000-Meter Run | 18:13.57 | Annie Cekada | Feb. 26, 2010 |
| 55-Meter Hurdles | 8.74 | Sarah Murphy | Jan. 31, 2015 |
| 60-Meter Hurdles | 9.10 | Sarah Murphy | March 6, 2015 |
| 4-x-200-Meter Dash | 1:46.35 | Denise Reinhard, Brooke Cotrell, Rose Bataille, Dana Crow | Feb. 22, 2002 |
| 4-x-400-Meter Dash | 4:02.07 | Denise Reinhard, Brooke Cotrell, Dana Crow, Emily Herring | Feb. 22, 2002 |
| 4-x-800-Meter Run | 9:48.64 | Jessica Unger, Brittany Wolf, Emily Herring, Kara Braun | March 2, 2001 |
| Distance Medley (1,200m, 400m, 800m, 1,600m) | 12:51.18 | Kelsey Stief, Krystal Taylor, Anna Foote, Annie Cekada | Feb. 26, 2010 |
| High Jump | 6-0 | Nyhla Rothwell | Feb. 13, 1999 |
| Pole Vault | 12-4.5 | Ashley Johnson | March 2, 2007 |
| Long Jump | 18-0.5 | Doreen Nagawa | March 5, 2005 |
| Triple Jump | 39-9.75 | Doreen Nagawa | March 12, 2005 |
| Shot Put | 44-1.5 | Marissa Bolen | Feb. 5, 2015 |
| Weight Throw | 56-10.25 | Lauren Stacy | Jan. 9, 2018 |
| Pentathlon | 2,867 pts. | Carrie Grimshaw | Jan. 15, 1998 |
*(>200m) refers to indoor tracks longer than 200 meters
*(=<200m) refers to indoor tracks shorter than 200 meters
*The office of athletic communications makes a concerted effort to keep these records accurate. If you have information that could assist this page, please contact Mitch Blankespoor, director of athletic communications, at mitch_blankespoor@wilmington.edu.
*Last updated - March 4, 2022